Despina is a distinctive girls' name in United States, ranking #15508 in 2025 with 5 recorded births. The name reached its all-time peak in 1998 with 20 births ranking #5193. Since 1996, the popularity has decreased by 68.8%. In 2025, approximately 1 in every 321,453 girls born was named Despina. FALLING Recent data shows the name is currently falling.