Isai is a distinctive boys' name in United States, ranking #953 in 2012 with 212 recorded births. The name reached its all-time peak in 2007 with 333 births ranking #701. Since 1996, the popularity has increased by 42.3%. In 2012, approximately 1 in every 8,946 boys born was named Isai. STABLE Recent data shows the name is currently stable.