Isai is a distinctive boys' name in United States, ranking #1053 in 2018 with 193 recorded births. The name reached its all-time peak in 2007 with 333 births ranking #701. Since 1996, the popularity has increased by 29.5%. In 2018, approximately 1 in every 9,407 boys born was named Isai. STABLE Recent data shows the name is currently stable.