Isai is a distinctive boys' name in United States, ranking #1170 in 2021 with 168 recorded births. The name reached its all-time peak in 2007 with 333 births ranking #701. Since 1996, the popularity has increased by 12.8%. In 2021, approximately 1 in every 10,406 boys born was named Isai. STABLE Recent data shows the name is currently stable.