Isis is a distinctive girls' name in United States, ranking #1625 in 2025 with 128 recorded births. This places Isis in the top 9% of ranked US girls' names for the year. Its actual usage is classified as Rare. The name reached its all-time peak in 2005 with 561 births ranking #522. Since 1996, the popularity has decreased by 41.3%. In 2025, approximately 1 in every 12,557 girls born was named Isis. FALLING Recent data shows the name is currently falling.