Karlene is a distinctive girls' name in United States, ranking #7047 in 2003 with 16 recorded births. The name reached its all-time peak in 1996 with 32 births ranking #3533. Since 1996, the popularity has decreased by 50.0%. In 2003, approximately 1 in every 114,191 girls born was named Karlene. RISING Recent data shows the name is currently rising.