Karlene is a distinctive girls' name in United States, ranking #7309 in 2006 with 17 recorded births. The name reached its all-time peak in 1996 with 32 births ranking #3533. Since 1996, the popularity has decreased by 46.9%. In 2006, approximately 1 in every 111,828 girls born was named Karlene. RISING Recent data shows the name is currently rising.