Karlene is a distinctive girls' name in United States, ranking #8537 in 2017 with 13 recorded births. The name reached its all-time peak in 1996 with 32 births ranking #3533. Since 1996, the popularity has decreased by 59.4%. In 2017, approximately 1 in every 132,760 girls born was named Karlene. RISING Recent data shows the name is currently rising.