Serene is a distinctive girls' name in United States, ranking #2483 in 2001 with 63 recorded births. The name reached its all-time peak in 2025 with 130 births ranking #1609. Since 1996, the popularity has increased by 53.7%. In 2001, approximately 1 in every 28,580 girls born was named Serene. STABLE Recent data shows the name is currently stable.