Serene is a distinctive girls' name in United States, ranking #2805 in 2004 with 58 recorded births. The name reached its all-time peak in 2025 with 130 births ranking #1609. Since 1996, the popularity has increased by 41.5%. In 2004, approximately 1 in every 31,657 girls born was named Serene. STABLE Recent data shows the name is currently stable.