Serene is a distinctive girls' name in United States, ranking #2972 in 2006 with 58 recorded births. The name reached its all-time peak in 2025 with 130 births ranking #1609. Since 1996, the popularity has increased by 41.5%. In 2006, approximately 1 in every 32,777 girls born was named Serene. STABLE Recent data shows the name is currently stable.