Serene is a distinctive girls' name in United States, ranking #2565 in 2007 with 73 recorded births. The name reached its all-time peak in 2025 with 130 births ranking #1609. Since 1996, the popularity has increased by 78.0%. In 2007, approximately 1 in every 26,335 girls born was named Serene. STABLE Recent data shows the name is currently stable.