Serene is a distinctive girls' name in United States, ranking #2416 in 2018 with 75 recorded births. The name reached its all-time peak in 2025 with 130 births ranking #1609. Since 1996, the popularity has increased by 82.9%. In 2018, approximately 1 in every 22,672 girls born was named Serene. STABLE Recent data shows the name is currently stable.