Spence is a distinctive boys' name in United States, ranking #5607 in 1999 with 12 recorded births. The name reached its all-time peak in 2005 with 20 births ranking #4439. Since 1996, the popularity has increased by 50.0%. In 1999, approximately 1 in every 160,007 boys born was named Spence. FALLING Recent data shows the name is currently falling.