Spyridon is a distinctive boys' name in United States, ranking #14049 in 2022 with 5 recorded births. The name reached its all-time peak in 1996 with 7 births ranking #7855. Since 1996, the popularity has decreased by 28.6%. In 2022, approximately 1 in every 348,875 boys born was named Spyridon. FALLING Recent data shows the name is currently falling.